منابع مشابه
P-98: Effect of Mouse Embryo Vitrification on Histone Modifications
Background: Vitrification has been usually used as an assisted reproductive technology in animals and humans. This method needs high concentrations of cryoprotectants that can be toxic with high cooling degrees. Then, vitrification could be change histone modifications such as methylation and acetylation can performance as regulatory controls of gene transcription. So, the purpose of the presen...
متن کاملCrosstalk among Histone Modifications
Histone modifications play a complex role in the regulation of transcription. Recent studies (Duncan et al., 2008; Lee et al., 2007; Li et al., 2008) reveal that regulation of histone modifications can be functionally linked to reinforce the activation or repression of gene expression.
متن کاملHistones and histone modifications
Imagine trying to stuff about 10,000 miles of spaghetti inside a basketball. Then, if that was not difficult enough, attempt to find a unique one inch segment of pasta from the middle of this mess, or try to duplicate, untangle and separate individual strings to opposite ends. This simple analogy illustrates some of the daunting tasks associated with the transcription, repair and replication of...
متن کاملSnapShot: Histone Modifications
H2B H3N-PEPAKSA...PKKGSKKAVTKAQKKD...RKRSRKE SYS...YKVLK ...TGISSK...S...SEASRLAHYNKRSTITSRE...VRL ...AKH...GTKAVTKYTSAK-COO10 20 29 30 42 52 64 75 80 90 98 107 114 120 100 Ar Ph Ph Ac Ar Ph OH Ph Ph Ph Ph Me OH Me Ph Ph Ph Me Me Ph Ph Ac Me/Ac/Bu/Cr Hib/Su/Fo Ac Bu Cr Me Ac Bu Cr Hib Me Ac Bu Cr Ac Bu Cr Me/Ac/Bu Cr/Hib/Ub Me Ac Bu Cr Hib Ac Hib Me/Cr/Hib Su/ Ub / Fo Ph Og Me Ac Hib Su Fo Me/A...
متن کاملGlobal effects of histone modifications.
The relationship between chromatin structure and transcriptional regulation has been the focus of many research publications over the past few years. A lot of progress has been made in understanding the role of histone modifications. The interdependence of histone methylation and DNA methylation has been revealed. Methylation, acetylation, phosphorylation and ubiquitination of specific histone ...
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ژورنال
عنوان ژورنال: Oncogene
سال: 2011
ISSN: 0950-9232,1476-5594
DOI: 10.1038/onc.2011.121